Natural na produkto
An natural na produkto iyo an sarong natural na compound o substance na prinodusir nin sarong buhay na organismo—boot sabihon, manunumpungan sa naturalesa.[1][2] Sa mahiwas na sentido, an mga natural products kabali sa maski arin na substance na prinodusir nin buhay.[3][4] An mga natural products pwede man na ipreparar sa paagi kan chemical synthesis (semisynthesis asin total synthesis asin ginampanan an sentral na papel sa pagpaurog kan lado nin organic chemistry sa paagi kan magtao nin maka-agyat na synthetic targets). An terminong natural product pinalakop para sa mga komersyal na katuyuhan tanganing magpanungod sa kosmetiko, dietary supplements, asin mga kakanon na prinodusir gikan sa natural na mga gunuan na mayong dugang na artipisyal na mga sangkap.[5]
An mga natural na gunuan posibleng maggiya sa basic research sa potensyal na bioactive components para sa komersyal na pagpaurog bilang lead compounds sa drug discovery.[6] Minsan ngani an mga natural products nakapag-inspirar nin nagkapirang mga bulong, drug development gikan sa mga natural na gunuan nakaresibi nin nagdidikit na atensyon kaidtong ika-21 na siglo kan mga kompanyang pharmaceutical, nin kabtang huli sa unreliable access asin suplay, intellectual property, gastos, asin profit concerns, seasonal o environmental variability nin komposisyon, asin an kawàran nin gunuan huli sa naghahalangkaw na pagkapuho.[6] Sa ibong kaini, an mga natural products asin an saindang derivatives na accounted man giraray sa haros 10% nin bagong pag-apruba nin mga bulong sa pag-ultanan kan 2017 asin 2019.[7]
Toltolan
[baguhon | baguhon an source]- ↑ Webster's Revised Unabridged Dictionary (1913). "Natural product". Free Online Dictionary and C. & G. Merriam Co.
A chemical substance produced by a living organism; – a term used commonly in reference to chemical substances found in nature that have distinctive pharmacological effects. Such a substance is considered a natural product even if it can be prepared by total synthesis.
- ↑ "All natural". Nature Chemical Biology 3 (7): 351. July 2007. doi:. PMID 17576412. "The simplest definition for a natural product is a small molecule that is produced by a biological source.".
- ↑ Samuelson G (1999). Drugs of Natural Origin: A Textbook of Pharmacognosy. Taylor & Francis Ltd. ISBN 978-91-86274-81-8.
- ↑ National Center for Complementary and Integrative Health (13 July 2013). "Natural Products Research—Information for Researchers | NCCIH". U.S. Department of Health & Human Services. Archived from the original on 5 April 2015.
Natural products include a large and diverse group of substances from a variety of sources. They are produced by marine organisms, bacteria, fungi, and plants. The term encompasses complex extracts from these producers, but also the isolated compounds derived from those extracts. It also includes vitamins, minerals and probiotics.
Unknown parameter|url-status=ignored (help) - ↑ "About Us". Natural Products Foundation. Retrieved 7 December 2013.
Natural products are represented by a wide array of consumer goods that continue to grow in popularity each year. These products include natural and organic foods, dietary supplements, pet foods, health and beauty products, "green" cleaning supplies and more. Generally, natural products are considered those formulated without artificial ingredients and that are minimally processed.
- 1 2 "Drug discovery and natural products: end of an era or an endless frontier?". Science 325 (5937): 161–165. July 2009. doi:. PMID 19589993. Bibcode: 2009Sci...325..161L.
- ↑ "Natural Products as Sources of New Drugs over the Nearly Four Decades from 01/1981 to 09/2019". Journal of Natural Products 83 (3): 770–803. March 2020. doi:. PMID 32162523. "Figure 1. All new approved drugs 01JAN81 to 30SEP19; n = 1881. Figure 9. N/NB/ND & S* categories 01JAN81 to 30SEP19, n = 506.". Natural products represent 100*(506/1881) = 27% of new drug approvals from 01JAN81 to 30SEP19. From Figure 9, the percentage was ~10% for 2017-2019.
